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Our findings of this meta-analysis are that the beneficial effects have been shown by the increase of overall efficacy, LVEF, strike volume, cardiac output, and E/A, by the decrease of left ventricular end-diastolic diameter, left ventricular end-systolic diameter, and left ventricular end-systolic volume and serum levels of BNP and NT-proBNP, and with satisfactory safety

Bellinghieri, G., Savica, V., Barbera, C

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