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The peroxynitrite-mediated activation of ERK committed bronchial (922) and neural cells (645, 1099, 1420) to apoptotic cell death, while activation of JNK, p38, or both triggered a similar outcome in murine alveolar cells (1162), cerebrocortical neurons (120), and PC12 cells (1148), respectively

In addition to promoting OxS, high-calorie/fat diets are also problematic because they are likely an initiating factor for prediabetes (see below) and promote overweight and obesity

Gefitinib enhances arsenic trioxide (AS 2 O 3 )-induced differentiation of acute promyelocytic leukemia cell line

Fis1 is required for the development of the dendritic mitochondrial network in pyramidal cortical neurons