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Vascular endothelial growth factor (VEGF)-A is a 45 kDa homodimeric glycoprotein and the most potent and specific regulator of physiological and pathological angiogenesis 8

Thus, the events in the rats after removal of the bilateral carotid artery ligation may be the followup of the observed activation of particular pathways with local and systemic relevance in the rats with ligation of the inferior caval vein receiving BPC 157 therapy (Vukojevic et al., 2018)

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