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It remains unknown if mfrn-2 levels are altered in FRDA patients, although skeletal muscle biopsies of ISCU myopathy patients and siRNA-ISCU fibroblasts transcriptionally upregulate mfrn2 (Crooks et al., 2014)
doi: 10.1186/s12864-017-4148-x 60 YeJCoulourisGZaretskayaICutcutacheIRozenSMaddenTL
