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Critically, in vivo studies confirm kaempferols translational potential, as it disrupts the MAPK/MMP-9 signaling cascade to prevent lung metastasis in murine melanoma B16F10 models (Lamouille et al., 2014)

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Recent literature reports that MnO 2 NPs have been extensively studied as O 2 deliver candidate because of their exceptional physio-chemical and biological properties, and highly sensitive to Hydrogen ion (H + ) and hydrogen peroxide (H 2 O 2 ), which are rich in tumors (Fatima, 2024