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Excitotoxicity is known to play a prevalent role in the pathogenesis of multiple neurodegenerative diseases, including ALS, and is intimately linked with both oxidative and nitrosative stress [65]

Research shows effectiveness across multiple wound types including incisional, excisional, thermal burns, chemical burns, and diabetic ulcers

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Activated calpains can aberrantly cleave several proteins that are critical for the integrity of neurons, such as spectrin, tubulin, tau, microtubule-associated protein, and neurofilaments (Wang and Po-Wai, 1994)