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[DOI] [PubMed] [Google Scholar] 75.Vadher K, Patel H, Mody R, Levine JA, Hoog M, Cheng AY, et al

Within body tissues, the specific B12 binding proteins transcobalamin I and II facilitate the absorption of cyanocobalamin into the cells.1017 Cyanocobalamin is a cofactor for the synthesis of two major enzymes in the body namely methionine synthase and L-methymalonyl-CoA mutase

Rotate sites systematically using a pattern (e.g., alternating between right/left abdomen, right/left thigh) to avoid lipohypertrophy and maintain consistent absorption [9]

Skin adverse reactions were also reported, such as injection site pain, pruritus, rash, and urticaria, but only a few cases of acneiform eruptions [5]