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For intracellular ROS measurement following stimulation with PMA (100 nM), luminol (50 M, A8515, Sigma-Aldrich) was added to the cell suspension along with membrane-impermeable superoxide dismutase (SOD

466 Given the known limitations of reaction parameters, synthesis design tools, synthetic strategies, and innovative chemistries, there are opportunities for expanding the synthetic toolbox of medicinal chemists

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Male reproductive tissues, such as the epididymis and testis [31,87], exhibit higher concentrations of L-Carnitine compared to plasma, highlighting its relevance to sperm maturation [88] and motility [89]