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While sustained astrocyte activation is often seen as detrimental, recent evidence highlights their reparative roles, including HO-1 production, metabolic support to OPCs, and recruitment of phagocytes for myelin debris clearance ( 4.2 Conclusion and future perspectives In summary, this study provides the first integrative temporal characterization of gutbrain axis components in the CPZ model of reversible demyelination

doi: 10.1016/j.expneurol.2017.05.010

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