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Description
At the molecular level, TQ molecule induces cell cycle arrest by inhibiting the cyclin E and cyclin D activation while upregulating other cell cycle inhibitors such as p21 and p27, leading to G1-phase arrest
The transamination product is expected to be a precursor of methylthiolactate and methylthioacetate
Cell 116 , 205219 (2004)
10.1016/s0939-6411(00)00087-4 223 MutluG.BudingerG.ScottR
