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Testosterone is the primary male sex hormone, produced predominantly by the Leydig cells in the testes under the direction of the hypothalamic-pituitary-gonadal (HPG) axis
These limited reports suggest good tolerability, though the small sample sizes, lack of standardized safety monitoring, and retrospective or uncontrolled study designs limit definitive safety conclusions
[9] It is on the World Health Organization's List of Essential Medicines
