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Description
Treatment of hyperkinetic movement disorders

Hippo signaling regulates YAP primarily through large tumor suppressor kinases 1 and 2 (LATS 1/2), which are activated through phosphorylation by mammalian sterile 20-like protein kinases 1/2 (MST1/2)

PMID: 117 SunSGuoCGaoTMaDSuXPangQet al

Domain Structure and Signaling Components of HGF-MET Pair Hepatocyte growth factor is produced and secreted as pro-HGF, representing the inactive precursor, and then activated by proteolytic processing in the extracellular milieu (Naldini et al., 1992)
