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Description
Nucleic Acids Research
This includes upregulation of antioxidant enzymes (superoxide dismutase, catalase) that protect against oxidative damage, enhancement of growth factor expression (TGF-, VEGF, PDGF) that supports tissue repair, and suppression of inflammatory gene expression that contributes to chronic skin degradation
Studies on the effects of camptothecin on various human colorectal cancer cell types (HCT116) found that only a lower dose (20 nM) induced senescence [63]
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