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NLRP3 has emerged as a critical initiator of cardiovascular diseases and plays a significant role in AS formation 32

Hbx sensitizes cells to oxidative stress-induced apoptosis by accelerating the loss of mcl-1 protein via caspase-3 cascade

Treatment with 250 and 500 mg/kg b.w of hydroalcoholic extract of dates daily for 14 days against LPS-induced sickness behavior in rats demonstrated reduced oxidative stress and neuroinflammation by decreasing the levels of IL-6 and TNF- levels in the brain and improved behavior (84)
