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A study in the Journal of Clinical Biochemistry says, Vitamin B12 deficiency can cause big problems with nerves and blood. Vitamin B12 is key for making DNA, fatty acids, and energy. Source: Journal of Clinical Biochemistry Common Signs of Deficiency A Vitamin B12 shortage can show in many ways, like: Fatigue and weakness Numbness or tingling in hands and feet Difficulty walking Mood changes, such as depression Spotting these signs early is key for quick action

They do not receive the same level of FDA approval as regular medications, and self-reported issues with dosing have been common

Hepatotoxicity (elevated liver enzymes, liver failure)

Deeper layers remain untouched