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Consistent with these observations, single-cell and spatial transcriptomic analyses of AD brains repeatedly reveal downregulation of mitochondrial and bioenergetic gene programs within excitatory neuron populations (Zou et al., 2024)

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These modified ARC reactors operate with a transition-metal catalyst that require a flowing O2gas (such as high purity Zero Air or He/1%O2blendat ~0.3 ml/min mixed into the He carrier gas) to enable complete conversion to CO2at lower temperature (620C) with acceptable reactor life, reduced complexity, and improved robustness

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