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Importantly his theory and its subsequent development and experimental testing were pivotal to the foundation of modern cellular immunology
10.1016/j.jneuroim.2009.12.003
DON treatment activates AMPK in cancer cells by increasing the AMP/ATP ratio and decreasing the expression of c-Myc proteins, thereby inhibiting glycolytic metabolism and suppressing cancer cell growth in vitro 145
With the growing appreciation of bile acids as signaling molecules, considerable study is being directed toward understanding the physiological functions of TGR5
