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AOD 9064, requires further research and testing for conclusive results

Additionally, both the antidepressant esketamine and the dextromethorphan-bupropion combination, approved by the US FDA, function through a shared mechanism that involves the activation of glutamatergic signaling in the prefrontal cortex [9-11]

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[DOI] [PubMed] [Google Scholar] 94.Vermaak I, Hamman JH, Viljoen AM