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Therapeutic interventions that target CNS-resident cells have been limited by the challenge of delivering drugs across the BBB, as NTFs pass the BBB only to a limited extent (140, 141)

[DOI] [PubMed] [Google Scholar] Ezzet F, Krishna G, Wexler DB, Statkevich P, Kosoglou T, and Batra VK (2001) A population pharmacokinetic model that describes multiple peaks due to enterohepatic recirculation of ezetimibe

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