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Electrochemical biosensors: Miniaturized electrochemical sensors incorporating glutathione-responsive nanomaterials (gold nanoparticles, carbon nanotubes, graphene oxide) offer the potential for continuous, real-time glutathione monitoring in perfused tissue models and organ-on-a-chip systems

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The researchers utilized the Achilles functional index (AFI), myeloperoxidase activity, histological inflammatory cell influx, and vascular index as potential markers

This distinction matters because tissue organization directly determines mechanical function and long-term durability