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The Wnt/-catenin signaling pathway target genes Lgr6 , lef1 , and Tcf7 (Lien et al., 2014) showed elevated expression, while the expression of Wnt inhibitors Sfrp4 , Sfrp5 , and Dkk1 ( Our network pharmacology analysis suggested that anwuligan promotes hair follicle regeneration by activating the Wnt/-catenin signaling pathway, potentially through direct binding to CTNNB1
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By combining different immunogens on the same mosaic nanoparticle, we then tried to mitigate the anti-HVR1 response
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