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Both increased production of ROS, as well as decreased antioxidant function have been shown to mediate the increased accumulation of cellular ROS [7]

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Descoberta [editar | editar cdigo] Foi descrito pela primeira vez, em 1888 por Rey-Pailhade, como philothion, designando simplesmente algo que continha enxofre, posteriormente cristalizado por diversos investigadores, onde se verificou a presena relevante deste elemento, sendo assim designado de glutationa (L-gama-glutamil-L-cisteinilglicina) [4]