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Functional role of mitochondrial reactive oxygen species in physiology

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Age-related increases or decreases of specific CYP isoforms and their activity can result in dysregulated steroid hormone synthesis and metabolism, leading to excessive accumulation or deletion of various hormones as CYP isoforms within the CYP11, CYP17, CYP19, and CYP21 families are involved in steroid biosynthesis
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