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LOS suppressed these AngII-mediated responses, whereas the AngII-independent upregulation of EMT-related proteins and the enhancement of mitochondrial energy metabolism by AngII in AGTR1-overexpressing cells remained unaffected

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[128] Though the film was a box-office bomb, [129] Us Weekly writer Mara Reinstein thought that Pattinson's performance in the film was "compelling", [130] while The Guardian thought that Pattinson was "considerably more interesting to watch", commenting that the viewer may find themselves "wishing that his character, rather than the dashing but dull Fawcett, was the focus of the film"

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