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DSIP interacts with endogenous receptor systems and has been investigated for its influence on the hypothalamicpituitaryadrenal axis, positioning it as a signaling pathway modulator in stress-response and neuroendocrine research models [1]

doi: 10.1016/j.physbeh.2014.10.033 259 WangLChristophersenCTSorichMJGerberJPAngleyMTConlonMA
"(The discovery) has boosted interest since the death of the cell is induced by its own iron content (which damages cell membranes)

doi: 10.1016/j.siny.2017.07.006