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Monoglutamate, but not polyglutamate forms are substrates to several folate-transporting proteins and are able to cross plasma membranes 275,876 or mitochondrial membranes 877,878

A new review by Sebastin Zagmutt Caroca PhD, Biotechnology Rosalia Rodriguez Rodriguez et al proposes a compelling framework positioning chronic hypothalamic microinflammation as an initiating eventnot a downstream consequenceof systemic metabolic dysfunction and #obesity

PMID: 18360646
