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Moreover, we summarize the current evidence supporting the use of TCM to target ferroptosis for improving UC, aiming to provide a new theoretical perspective for future research on the potential roles of TCM compounds and formulas with similar capabilities to target ferroptosis in the treatment of UC

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On the contrary, C57BL/6 mice injected subcutaneously with Nrf2 knockdown Hepa16 cells showed a decrease in tumor size and diminished NQO1 and HO-1 mRNA expression after sorafenib administration when compared to Nrf2 -shRNA control mice [309]

Among these, AHK-Cu has been posited to potentially both extend and trigger Anagen hair growth phases, with impacts in certain research studies reported up to 3-5 years