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the consequences of pharmacologic NNMT inhibition in users with subclinical malignancy are uncharacterized
NNMT takes nicotinamide, a form of vitamin B3, and attaches a methyl group to it, using SAM (S-adenosylmethionine) as the methyl donor
NNMT inhibition increases NAD+ levels and enhances sirtuin-mediated mitochondrial function
