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Description
Epithalon has demonstrated a good safety profile in experimental and limited human studies, showing minimal adverse effects when used properly in research settings
(a) and (b) Distribution diagram for 2,3-DHBA (a) and 3,4-DHBA (b) at 293 K (solid black lines) and 281 K (dotted red lines) in 0.010 M NaCl medium at a total DHBA concentration of 0.001 M
However, the magnitude of 5-oxoprolinuria that occurs under these conditions is modest and overt metabolic acidosis does not develop (52,53)
Inflammation likely plays a part in several of these effects, but the exact biology in humans is still not well understood