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Meanwhile, Nrf2 regulates the production of mitochondrial ROS by enhancing the biosynthesis of glutathione and the activity of glutathione reductase, up-regulating the enzymes in the pentose phosphate pathway, and regulating the expression level of mitochondrial antioxidant enzymes, thereby protecting mitochondria from oxidative damage (Ebrahimy et al., 2022
doi: 10.1093/annonc/mdz167 144 SkoulidisFGoldbergMEGreenawaltDMHellmannMDAwadMMGainorJFet al
The polyploid state plays a tumor-suppressive role in the liver
Predictive metabolomic signatures for safety assessment of metal oxide nanoparticles
