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[DOI] [PubMed] [Google Scholar] 78.Taschler U, Schreiber R, Chitraju C, Grabner GF, Romauch M, Wolinski H, et al
Chronic pain may reflect nerve injury, musculoskeletal disease, recurrence, scar, fixation material, or unrelated neuropathic conditions
It also impairs parathyroid hormone release, leading to secondary hypocalcemia
Previous studies have reported that PKM2 is enzymatically active toward pyruvate only as a tetramer and acts as a transcription factor coactivator when tetrameric PKM2 dissociates into a dimer 28,29
