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In addition, TMAO induces several inflammatory pathways, which cause the activation of pro-inflammatory cytokines such as IL-6 and TNF- which causes chronic inflammation thereby causing plaque formation and plaque rupture leading to cardiovascular disease [71]
Determination of serum biochemical parameters Serum Malondialdehyde (MDA) (nmol/ml), as an indicator of lipid peroxidation [29], was quantified by a thiobarbiturate reactive substance method, as previously described [30]
Vanessa Fiorentino, T., A
