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Preclinical studies demonstrate that BefA increases -cell mass by promoting both neogenesis from endocrine progenitors and proliferation of mature -cells (Hill et al., 2022)

Chem Pharm Bull (Tokyo) 1983;31:179185

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Treatment with DMOG induced beneficial effects, with lowered bacterial burden due to the metabolic reprogramming of macrophages via HIF-1 pathway activation in vitro and in vivo (244)
