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Description
Nakamura T, Sugiura S, Kobayashi D, et al

Signaling via NF-B and MAPK pathways drives pro-inflammatory cytokine gene expression (37), while a concurrent shift to aerobic glycolysis stabilizes HIF-1, which further amplifies the transcription of cytokines like IL-1 (63, 66)

The trial lasted for 45 days

HLA-DR15 molecules jointly shape an autoreactive T cell repertoire in multiple sclerosis
