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Description
Anti-Inflammatory Activity The anti-inflammatory mechanism of ketorolac is due to decreased prostaglandin synthesis via inhibition of COX-1 and COX-2

Interestingly, Choi and colleagues described decreased hepatic GSH levels, which correlated with a fall in GS activity in Tat transgenic mice (Choi et al., 2000)

10.1039/D4FO01142B

Studies show that TIGAR knockdown can lead to increased ROS accumulation, resulting in DNA damage and cell senescence, and significantly enhances the sensitivity of glioma cells to radiotherapy, making TIGAR a potential therapeutic target [206]
