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318,322 Macrophages have two polarization states, M1 typically has pro-inflammatory properties, while M2 has anti-inflammatory properties
It has a crucial role in regulating mitochondrial respiration, ROS clearance, lipid metabolism, fatty acid oxidation, and antioxidant activity (Weerawatanakorn et al., 2023)
Prescribers should be aware that hydroxocobalamin is contraindicated in patients with a known hypersensitivity to cobalt or any other component of the injection solution

It is an endogenous peptide-copper complex identified in biological systems
