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While it doesnt contain retinoids, it pairs well with retinoid regimens by targeting puffiness through melatonin, caffeine, and antioxidant support, says Pooja Rambhia, MD, a board-certified dermatologist based in New York City

Ufnal et al., 2014)

Mechanical ventilation may be necessary in patients who require airway protection or who develop cerebral oedema or respiratory depression

10.1016/j.theriogenology.2016.02.034 2