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In patients with more severe disease, dual bronchodilators (LABA + LAMA) show superiority over placebo or either of the drug alone in reducing ECOPD 54,55

ELISA assays complement the HPLC analysis by measuring concentrations of melatonin and neurotrophic factors, utilizing kits from Sangon Biotechnology Company (Shanghai, China) following strict protocols to ensure reliability

57 Short-acting bronchodilators should be prescribed for immediate symptom relief, but not recommended for chronic use

[DOI] [PubMed] [Google Scholar] 93.Jee D., Park M., Lee H.J., Kim M.S., Kim E.C
