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It is worth noting that the increase in Nrf2 DNA binding activity induced by berberine can be antagonized by PI3K inhibitors and AKT inhibitors

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Accompanying these neural stem/progenitor and neuronal effects, the exposure to young blood led also to greater vascular density, not only in the neurogenic niches but throughout most of the brain

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Hseu JH, Chan CI, Vadivalagan C, Chen SJ, Yen HR, Hseu YC, Yang HL, Wu PY

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