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Contois, J

10.1016/j.tem.2008.02.005 96 MagnerD

Membranes linked by trans -SNARE complexes require lipids prone to non-bilayer structure for progression to fusion

In addition, Sptlc2 deletion in UCP1-expressing cell types reduces fat mass and enhances energy expenditure along with improving insulin tolerance, suggesting that ceramides in thermogenic adipocytes contribute to impaired thermogenesis and the development of obesity
