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Model building refinement and validation Individual domains of dmIR-ECD were predicted using AlphaFold/2.0.0-foss-2020b 70 and docked as rigid bodies into the 4.0 resolution cryoEM maps using UCSF Chimeras Fit in map function 71

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Defined: Ectopic pregnancy refers to implantation of the zygote outside the uterus or in an abnormal location within the uterus

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