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It is often classified as a conditionally essential nutrient, which means your body can produce it under normal circumstances, but supplementation may be necessary in certain cases

doi: 10.3389/fendo.2015.00136

MolProbity: all-atom contacts and structure validation for proteins and nucleic acids

Mientras que el efecto protector del folato contra DTN est bien establecido, solo unos pocos estudios han investigado el papel de otros donantes de grupos metilo, incluyendo colina y betana, en la aparicin de DTNs
