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Sorafenib induced acral pigmentation: a new entity

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Immunosuppressive agents, such as azathioprine, methotrexate, cyclophosphamide, and mycophenolate mofetil, are equally disappointing in our experience in spite of rare anecdotal reports

But in the cytosol, even during oxidative stress, the ratio of GSH/GSSG remains very high, which makes that exchange reaction unfavorable
