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Prescription opioids caused 16,416 reported deaths in 2020 and 16,706 overdose deaths in 2021

For example, the senescence of cardiac endothelial cells may exacerbate myocardial ischemia and heart failure

The development of novel delivery systems, such as nanoparticles and encapsulated extracts, may enhance bioavailability and therapeutic efficacy, addressing a significant limitation in its pharmacological application

Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c
