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Park E, Na M, Choi J, Kim S, Lee JR, Yoon J, et al

Assessment of growth parameters and life span of GHR/BP gene-disrupted mice

Glutathione is synthesized in the cytosol of all cells from their precursor amino acids: glutamic acid, cysteine and glycine by consecutive action of two enzymes: -glutamyl-cysteine (-GluCys) synthetase (also known as glutamate cysteine ligase, GCL) that in a first step uses glutamate and cysteine as a substrate to form the dipeptide -glutamyl-cysteine