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May-Jun 1990;18(3):201-9

Editorial: nanomedicine-based drug delivery systems: recent developments and future prospects
Moreover, NO production in the vascular endothelium of the penis has been found to be decreased in vasculogenic ED, such as in the case of ED caused by atherosclerosis and diabetes [16, 17, 19], and a reduction of circulating l-ARG levels has been detected in patents with vasculogenic ED [20], further confirming that l-ARG supplementation might be beneficial in the treatment of vasculogenic ED
Murphy MP