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Herrera NA, Jesus I, Shinohara AL, Dionisio TJ, Santos CF, Amaral SL

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Quercetin has been shown to exert inhibitory effects on the key innate immune receptor TLR-2, thereby modulating the innate immune system.25 It has also been shown that quercetin has a modulatory effect on T-cell activation, with its ability to enhance IFN- secreted by Th1 cells and inhibit the Th-2-derived cytokine IL-4, which contributes to the enhancement of Th1 cell-mediated immune response (Li et al., 2016b)