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The GPx activity was determined as a function of the decrease in NADPH measured at 340 nm and normalized to hemoglobin content (for blood)

Since no appropriate PR3-AAV model exists, clinical studies with adjunctive DPP1 inhibitor administration in patients with PR3-AAV may provide the best approach to test this hypothesis

doi: 10.1016/j.bbr.2019.02.025
doi: 10.3390/biom11070982