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In recent decades, the following treatments for IC/BPS have been recommended as replenishment of the glycosaminoglycan layer to control urothelial defects, administration of amitriptyline or imipramine to inhibit neurological hyperactivity, suppression of allergies by antihistamines, and non-steroid anti-inflammatory drugs for pain control (Homma et al., 2020)

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The lower 5-GABA A receptor levels we observe may therefore contribute to reductions in tonic inhibition, leading to an increase in hippocampal hyperexcitability

Figure 5 Discussion A variety of eryptosis inducers have been used to study eryptosis of nave erythrocytes over the past 20 years