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91 Therefore, clinical studies on conservative treatment are lacking, and, likewise, the natural course is largely unknown

This frustration is why there are so many treatment options

Shakiba E, Bazi A, Ghasemi H, Eshaghi-Gorji R, Mehdipour SA, Nikfar B, Rashidi M, Mirzaei S

During this transitory phase methyl groups are formed from key nutrients including folic acid, B vitamins and s-adenosyl methionine (SAMe), and these methyl groups, as described earlier, comprise important epigenetic marks for gene silencing
