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91 Therefore, clinical studies on conservative treatment are lacking, and, likewise, the natural course is largely unknown

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This frustration is why there are so many treatment options

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Shakiba E, Bazi A, Ghasemi H, Eshaghi-Gorji R, Mehdipour SA, Nikfar B, Rashidi M, Mirzaei S

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During this transitory phase methyl groups are formed from key nutrients including folic acid, B vitamins and s-adenosyl methionine (SAMe), and these methyl groups, as described earlier, comprise important epigenetic marks for gene silencing

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